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创面愈合过程中EGFr基因表达的研究
STUDY ON THE CHANGE OF EXPRESSION OF EGFr GENE DURING THE WOUND HEALING
【摘要】 应用原位分子杂交技术观测了大鼠创面愈合过程中表皮生长因于受体(Epidermalgrowth factor receptor,EGFr)的信使核糖核酸(mRNA)表达的变化.结果表明:伤后4天EGFrmRNA即有明显的表达,以后逐渐减弱,伤后16天EGFr mRNA已无明显表达.对EGFr基因表达的作用和机理进行了讨论.
【Abstract】 The change of EGFr mRNA expression during the wound healing is determined with the in situ hybridization. The results show that EGFr mRNA is expressed obviously on the 4th day after being wounded and gradually decreased and not expressed on the 16th day. In this paper the function and mechanism of EGFr gene expression are also discussed.
【关键词】 表皮生长因子受体；
创面愈合；
原位分子杂交；
【Key words】 Wound healing； Epidermal growth factor receptor； In situ hybridization；
【Key words】 Wound healing； Epidermal growth factor receptor； In situ hybridization；
【基金】 国家自然科学基金资助项目
- 【文献出处】 中国组织化学与细胞化学杂志 ,Chinese Journal of Histochemistry and Cytochemistry , 编辑部邮箱 ,1996年02期
- 【分类号】R641
- 【被引频次】5
- 【下载频次】52