节点文献
2',3'-O-异亚丙基-5'-O-[N,N-二(2-氯乙基)磷酰胺基]核苷的合成
Synthesis of 5’-O-(N, N-Bis(2-chloroethyl) phosphoramide)-2’,3’,-O-isopropylidenenucleosides
【摘要】 2',3'-O-异亚丙基-5'-O-[N,N-二(2-氯乙基)磷酰胺基]核苷的合成陈茹玉,迟国臣,陈小茹(南开大学元素有机化学研究所,天津,300071)关键词核苷,亚磷酰化,抗肿瘤活性很多核苷类化合物具有很好的抗肿瘤、抗病毒等生物活性,某些化合物已...
【Abstract】 A number of new title compounds were synthesized.The structures of all the products had been confirmed by elementary analysis,1H NMR and IR.The results of preliminary biological tests indicated that the title compounds had the inhibition effect against HL-60 cell lines and BCap cell lines.
【基金】 国家自然科学基金
- 【文献出处】 高等学校化学学报 ,CHEMICAL RESEARCH IN CHINESE UNIVERSITIES , 编辑部邮箱 ,1996年03期
- 【分类号】O629
- 【被引频次】2
- 【下载频次】75