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丝素蛋白的构象转变

Conformation Transition of Silk Fibroin

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【作者】 于同隐张胜邵正中

【Author】 YU Tong-Yin;ZHANG Sheng;SHAO Zheng-Zhong (Department of Macromolecular Science and Laboratory of Molecular Engineering of Polymers,Fudan University,Shanghai,200433)

【机构】 复旦大学高分子科学系和聚合物分子工程开放实验室

【摘要】 丝素蛋白的构象转变于同隐,张胜,邵正中(复旦大学高分子科学系和聚合物分子工程开放实验室,上海,200433)关键词丝素蛋白,构象转变,扫描隧道显微镜桑蚕丝素蛋白是生丝的主要组分。蚕在作茧时,将体内水溶性的丝素蛋白排出体外,成为不溶性的茧丝,这一过程既...

【Abstract】 The conformation transition of silk fibroin in the silk glands of Bombyx mori was studied by scanning tunneling microscopy. The dilute aqueous solution of fibroin synthesized in the posterior glands is in a form of random coils,which are transformed into coiled-coil and later into individual α-helices in the middle glands.During spinning,they turned into β-strands and finally to β-sheets,The formation of liquid crystalline state aids the process of spinning.The STM images were taken dozens of time for each sample at different spots,which can represent the general nature of fibroin in the glands of silkworm.So far as we know,this is the first time to have the individual fibroin,or more specifically,the α-helix and β-sheet structure of protein,to be imaged.

【基金】 国家基础性研究重大项目,国家自然科学基金
  • 【文献出处】 高等学校化学学报 ,CHEMICAL RESEARCH IN CHINESE UNIVERSITIES , 编辑部邮箱 ,1996年02期
  • 【分类号】S881.3
  • 【被引频次】24
  • 【下载频次】457
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