【摘要】 １９８４年开始在广东省范围内开展地方性氟中毒流行病学调查及防治效果观察。结果广东省２１个地级市１１８个县（市）中有１７个市、４０个县有不同程度的地氟病流行。病区４４８个、病区总人口数为５７６４６７，约占全省总人口的１％。病区主要分布在粤东四个市（汕头、揭阳、潮州、梅州），病区数占全省的５２．７％，病区人口数占８６．９％。病区类型以饮水型为主（９５％），少数为温泉水污染食物型。造成地氟病流行的主要原因是广东境内富氟地质构造中的氟转移到居民饮用水源，引起水氟超标。饮水型病区经改水降氟后，水氟由改水前１２．５ｍｇ／ｌ降至０．３４ｍｇ／ｌ，改水后第七年８～１２岁儿童氟斑牙患病率由改水前９６％降至７３．３％．其尿氟含量（０．９６ｍｇ／ｌ）降至正常值以下。更多还原

【Abstract】 The study showed that endemic fluorosis was found in seventeen cities and forty counties in Guangdong Province. The total population of the areas was 576467, which accounted for about 1% of the population in the province. The endemic areas mainly located in four cities (Shan Tou,Jie Yang,Chao Zhou and Mei Zhou) in the eastern part of the province,and the number and population of the areas accounted for 52. 7% and 86. 9% of the province respectively. Most endemic areas (95. 5%) could be classified as areas caused by drinking water and just a few caused by food contaminated by hot-spring water. The main control measure of the disease is to change drinking water source and/or reduce its fluoride content. In the 7th year, a fier drinking water fluoride content reduced from 12. 5mg/L to 0. 34mg/L by changing water source, the prevelence of dental fluorosis in children aged 8 to 15 years decreased from 96% to 73. 3% and the urine fluoride content became normal.更多还原