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肺癌患者与正常人尿液精脒含量的比较

A Comparison Study of Urinary Spermidine Content in Lung Cancer Patients and Controls

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【作者】 张春晓

【Author】 Zhang Chunxiao(Department of Biochemistry,Fujian Mcdical University,Fuzhou,350004)

【机构】 福建医科大学生物化学教研室

【摘要】 目的探讨尿液精脒含量作为肺癌患者辅助诊断、预后、疗效评价指标的临床意义。方法采用聚酰胺薄层层析法测定尿液精脒含量。结果肺癌患者尿液游离精脒含量(111.22±10.82mg)较正常人(17.93±1.65mg)显著升高(P<0.01)。结论尿液精脒含量可作为肺癌患者辅助诊断、预后、疗效评价的指标。

【Abstract】 To investigate the clinical significance of the spermidine content in urine as an index of accessory diagnosis,prognosis and therapeutic effect evaluation for patients with lung cancer.Methods Polyamide thin layer chromatography is used to determine the spermidine content in urine.Results The spermidine content in the urine of cancer patients is found to be significantly higher than in that of normal people(P< 0.01).Conclusion Determination of spermidine content in urine can be used as an index of accessory diagnosis,prognosis and therapeutic effect evaluation for patients with lung cancer.

  • 【分类号】R734.204
  • 【下载频次】32
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