【摘要】 本文通过41例全子宫切除术，观察到所施硬膜外麻醉本身即可致一定的细胞免疫抑制。笔者按麻醉前、后及手术后分三期观察其T细胞亚群变化、结果表明其CD₃⁺、CD₄⁺细胞百分率逐期下降，但无统计学意义（P＞0.05）。CD₈⁺百分率则逐期上升，麻醉后切皮前上升值无意义（P＞0.05），术后与前两期相比上升均非常显著（P＜0.01）。CD₄⁺/CD₈⁺此值在麻醉后切皮前已明显下降（P＜0.01），而术后则下降更为显著（P＜0.001）。更多还原

【Abstract】 In 41 complete hysterectomy, We observed that epidural anesthesiaitself can produce some cell-mediated immunity suppresson. Variation in T lymphocyte subclases was investigated according to thee stages, . i. e. before anesthesia, after anesthesia (before incision) and first postoperative day. The results showed that both CD3+ percentage and CD4+ percentage decrease stage by stage, but all of them have not statistically significant (P>0. 05) On the other hand, CD8- percentage increases stage by stage. Moveover, its increase at the second stage has not statistically significant (P>0. 05), but at the third stage its increase has a higher degree of statistical significance (P<0. 01) than the first two stages. Meanwhile,CD4+/CD8+ ratio decreases significantly (P <0. 01) at the second stage, and the decrease is much more statistically significant (P<0. 001) at the third stage.更多还原