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胶束对几种Cu(Ⅱ)─氨基酸络合物SOD样活性的影响

THE EFFECT OF MICELLAR ON THE SOD- LIKE ACTIVITTES OF SEVERAL Cu(Ⅱ)-AMINO ACID COMPLEXES

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【作者】 金虬程志明李大珍

【Author】 Jin Qiu ;Cheng Zhiming; Li Dazhen (Department of Chemistry, Beijing Normal University, 100875, Beijing, PRC)

【机构】 北京师范大学化学系

【摘要】 测定了阳离子型表面活性剂CTAB和阴离子表面活性剂SDS在磷酸缓冲溶液(pH=7.8)中的临界胶束浓度CMC将自行制备的数种作为SOD模拟物的Cu(Ⅱ)氨基酸络合物分别置于胶束体系中,在pH=7.8及(20.0±0.5)℃条件下,用细胞色素C法测定了其对超氧阴离子自由基O歧化反应的催化活性。实验结果表明:当Cu(Ⅱ)-氨基酸络合物置于胶束体系后,除少数例外,SOD活性大多有所提高,其中以CTAB所形成的胶束对于提高Cu(Ⅱ)-氨基酸络合物的SOD样活性作用最为显著。对实验结果作了初步探讨。

【Abstract】 Abstract A cationic surfactant CTAB and an anionic snrfactant SDS were measured criti cal micelle concentration in phosphate buffer (pH=7.8) solution. Several Cu(Ⅱ) - amino acid complexes as analogues of SOD were placed in micellar system to form micelle-analogues.The catalytic activities of these micelle - analogues catalyzing dismutation of superoxide aninon radical (O) were measured by cytochros C method at (2a.a±a.5)℃ and pH=7.8. The experimental results showed: the SOD - like activities of analogues of SOD in micelle (exapt few analogues of SOD) are improved.That micelle of CTAB improves the SOD -like activities of Cu(Ⅱ)-amino acid complexes is very obvious. The experimental results were discussed.

【基金】 国家自然科学基金
  • 【文献出处】 北京师范大学学报(自然科学版) ,JOURNAL OF BEIJING NORMAL UNIVERSITY , 编辑部邮箱 ,1996年03期
  • 【分类号】R977.4
  • 【被引频次】6
  • 【下载频次】80
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