【摘要】 以辛酸亚锡为催化剂,1,4-丁二醇为引发剂,通过开环聚合,合成了双端为羟基,不同分子量、不同配比的(乙交酯-ε-己内酯)共聚酯。用红外、核磁、端基滴定、DSC等手段,对其组成、端基结构、分子量及热分析性能进行了测定,并进一步合成了以共聚酯为软段,4,4’-二苯甲烷二异氰酸酯-1,4-丁二醇链节为硬段的嵌段聚酯氨酯,进行了物性测定与体外降解试验,着重讨论了软段组成与分子量对嵌段聚氨酯性能的影响。更多还原

【Abstract】 A series biodegradable segmented polyester urethane (SPESU) weresynthesized.The soft segment was poly (glycolide-co-caprolactone) prepared byring-opening copolymerization of glycolide and e-caprolacton initiated by 1,4-bu-tanediol(BD) using stannous octoate as catalyst.The physical and structural char-acterizations were performed using FTIR,NMR,DSC,dynamic viscoelastic andstress-strain test.Prepared SPESU films were subjected to degradation at 37 °C inphosphate buffer solution of pH 7.2 in vitro.Experimental results showed that theeffect of GA content in poly (GA-co-CL)and soft segment molecular weight on thephysical properties and degradation rates of SPESU was obvious.更多还原