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粘膜相关淋巴组织淋巴瘤的细胞遗传学研究
CYTOGETIC STUDY ON B-CELL LYMPHOMAS OF MUCOSA-ASSOCIATED LYMPHOID TISSUE
【摘要】 对8例分别位于胃、小肠等部位的低度恶性的粘膜相关淋巴组织(MALT)的B细胞性淋巴瘤进行了染色体分析。结果发现染色体以结构畸变为主,分别涉及到2p ̄(11-13,7q ̄(21),10p ̄(13-15),11q ̄(13),12p ̄(11-12),14q ̄(32)以及16q ̄(24)等部位。此结果表明MALT淋巴瘤具有与淋巴结内的淋巴瘤相似的细胞遗传学特性,可能反映了B淋巴细胞淋巴瘤的共同的发病机理。
【Abstract】 Eight cases with low grade malignant B-cell lymphoma of mucosa-associated lymphoid tissue(MATL)in stomach and small intestine were studied cytogenetically.2p ̄(11-13),7q ̄(21),10p ̄(13-15),11q ̄(13),12p ̄(11-12),14q ̄(32) and 16q ̄(24) were found to be involved in different translocations.The results showed that MALT-lymphoma had similar cytogenetic characterizations of nodal malignant lymphoma and might sharethe common nechanism of B-cell tumors in origin.
【关键词】 粘膜相关淋巴组织;
淋巴瘤;
染色体畸变;
【Key words】 Mucosa-associated lymphoid tissue Lymphoma Chromosome aberration;
【Key words】 Mucosa-associated lymphoid tissue Lymphoma Chromosome aberration;
- 【文献出处】 癌症 ,CHINESE JOURNAL OF CANCER , 编辑部邮箱 ,1996年02期
- 【分类号】R733.402
- 【被引频次】1
- 【下载频次】35