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恶性淋巴瘤的肝脾侵犯──29例NHL尸体肝脾穿刺分析

HEPATIC AND SPLENIC INVOLVEMENT OF NON-HODGKIN’S LYMPHOMAS(NHL)An analysis of 29 cases with postmortem pathological study via needle aspirations of liver and spleen

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【作者】 许立功洪小南唐惟瑜

【Author】 Xu Li-gong,Hong Xiao-nan,Tang Wei-yu(Dept.of Chemotherapy,Tumor Hospital,Shanghai Medical University 200032)

【机构】 上海医科大学肿瘤医院化疗科

【摘要】 本文介绍29例NHL尸体的肝脾穿刺研究。肝穿刺29例,肝侵犯率79.3%。脾穿刺26例。脾侵犯率76.9%。有肝脾肿大的病例肝或脾侵犯率分别为71.4%和90%,无肝脾肿大的病例,肝或脾侵犯率分别为80.0%和68.75%。LDH显著升高和高热多见于肝侵犯病例。脾累及的病人常同时有肝累及,肝累及病人几乎均同时有脾累及。由于肝侵犯的证实,31%的病例分期上升。

【Abstract】 The result of pathological examinations of liver and spleen specimens obtained by postmortem needle aspirations of liver and spleen were reported.The incidence of hepatic involvement was 79.3% (22/29),while the incidence of splenic involvement was 76.9% (20/26).The incidence of hepatic and splenic involvement were 71.4% and 90% respectively,in cases with or without hepatomegaly or splenomegaly,the incidence were 80.0% and 68.75% respectively,conseqently the clinical hepatomegaly or splenomegaly was not a reliable sign for hepatic and splenic involvement in case of NHL,especially in stage Ⅲ and Ⅳ cases.Marked elevation of serum LDH activity and hyperpyrexia were frequently seen in NHL with hepatic or splenic involvement.Most of the cases with splenic involvement had hepatic involvement too,while patients with hepatic involvement nearly always had splenic involvement.After this procedure,upstaging was seen in 31% of our cases.

  • 【分类号】R733.1
  • 【被引频次】4
  • 【下载频次】38
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