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安榆止血粉对实验性胃溃疡模型的研究

Studies on Effect on An-Yu-Zhixuefen on Experimental GastricUlcer Models in Rats and Mice

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【作者】 杨解人李文明胡荣华陈国祥熊克仁

【Author】 Yang Jieren; Li Wenming; Hu Ronghua; Chen Guoqiang; Xiong Keren(Wannan Medical College, Wuhu 241001)

【机构】 皖南医学院

【摘要】 安榆止血粉0.214~0.856g/kg,qd,5~7d,ig,对应激性、组织胺性、水扬酸性和利血平性胃溃疡模型具有不同程度的抑制作用。溃疡抑制率分别为19.03~63.06%,51.26~84.54%,65.70~76.30%和33.60~64.75%,其中以对组织胺型和水扬酸型的保护作用尤为突出,对应激性溃疡作用较弱。

【Abstract】 n- Yu-Zhixuefen (AYZXF, 0.214-0.856g/kg qd, 5-7d, ig) was shown to be an effective anti-ulcer agentin four experimental models in rats and mice, namely the stress restraint--induced, histamine--induced, salicylic acidinduced and reserpine-induced ulcers. In four experimental models, AYZXF could inhibit gastric ulcer by 19. 03-63. 06%, 51. 26 ̄84. 54 %, 65. 70-76. 30% and 33. 60-64. 75% respectively. Among them, the histamineinduced and salicylic acid-induced ulcer were particularly markedly inhibited. The result suggested that AYZXF had theprotective action from the gastric peptic ulcer.

【关键词】 安榆止血粉胃溃疡
【Key words】 An-Yu-Zhixuefen: Gastric ulcer
【基金】 安徽省教委资助
  • 【文献出处】 中药药理与临床 ,PHARMACOLOGY AND CLINICS OF CHINESE MATERIA MEDICA , 编辑部邮箱 ,1995年04期
  • 【分类号】R285
  • 【下载频次】41
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