【摘要】 ＭｃＡｂＦ（ａｂ＇）_２免疫脂质体制备及其亲和性的放免测定刘健，陈正秋，刘汉芝，范启修，沈德诚，李树梅（中国医学科学院，中国协和医科大学，血液学研究所，天津３０００２０）脂质体作为药物载体可降低药物毒性，提高药效［１，２］。由ＭｃＡｂ制备的兔疫脂质体?..更多还原

【Abstract】 Abstract The F(ab’)2-DNR-liposomes were prepared using F(ab’)2 obtained from digested monoclonal antibody against human white cells HI30(CD45).Their affinity constant for peripheral blood mononuclear cells was determined by radioimmunoassay. Ka=2.0×109 .A good specific conjugation ability was dernonstrated. In preparing the immunoliposomes,it was found that F(ab’)2 coupled to the smaller liposomes with higher conjugation ratio.更多还原