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养阴方对实验性肝癌诱癌过程的影响

The Effect of Prescription of Nourishing Yin on Induced Course of Experimental Hepatocarcinoma

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【作者】 王晓素刘成刘平徐列明胡义杨朱剑亮梁新敏李风华

【Author】 Wang XiaoSu, Liu Cheng, Liu Ping et al. Research Center of Liver disease, Shanghai Academy of TCM (Shanghai, 200032)

【机构】 上海市中医药研究院肝病研究中心上海市中医药研究院肝病研究中心 200032200032200032

【摘要】 以DEN与AFB1诱发大鼠肝癌为模型,通过病理形态与生化指标的观察,发现养阴方能减少模型鼠肝细胞异型性增生灶,降低肝组织GGT、GST与血清ALP活性升高的幅度,提示药物对癌前期病变形成有较明显的抑制作用。

【Abstract】 Hepatocarcinoma model was induced in rats by diethylnitrosamine (DEN) and aflatoxin B1 (AFB1), and was observed by pathological picture and biochemical criterion. The result showed that the prescription of nourishing yin can reduce the dysplasia of hepatocyte in model rat, reduce the increase range of activity of GGT and GST in hepatic tissue, and it of ALP in serum. It showed that this prescription has remarkable inhibition to precan(?)erous lesioncerous lesion.

  • 【文献出处】 中西医结合肝病杂志 ,Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases , 编辑部邮箱 ,1995年01期
  • 【分类号】R273
  • 【被引频次】26
  • 【下载频次】64
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