【摘要】 传统心肺复苏成功率不高的原因之一是冠脉有效灌注压（ＣＰＰ）低，本文提出舒张期辅以增强型体外反搏（ＥＥＣＰ）（外周泵）的充气背心（ＶＥＳＴ）（中心泵）的新型复苏术（ＶＤＶＥＳＴ－ＣＰＲ）。以ＩＭＥＰＣ３８６为控制主机的多功能复苏装置，在８条犬心室颤动３０ｓ后随机地实施充气背心心肺复苏术（ＶＥＳＴ－ＣＰＲ）及ＶＤＶＥＳＴ－ＣＰＲ，自身对照设计。实验结果，ＶＤＶＥＳＴ－ＣＰＲ较ＶＥＳＴ－ＣＰＲ显著升高主动脉压和右房的舒张压（Ｐ＜０．０１）。主动脉舒张压升高程度较右房的舒张压大。故ＣＯＰ仍有效大幅度升高（Ｐ＜０．０１），ＣＰＰ峰值（６．８１±２．９５ｋｐａｖｓ４．０７±３．０５ｋＰａ），ＣＰＰ平均值（５．７６±２．６２ｋＰａｖｓ３．８７±２．８１ｋＰａ）。主动脉收缩压平均值也显著性升高（１０．６２±４．２３ｋＰａｖｓ９．３９±４．６１ｋｐａ，Ｐ＜０．０５）。结果表明，ＶＤＶＥＳＴ－ＣＰＲ既体现ＶＥＳＴ特点，又发挥了ＥＥＣＰ的长处。既有较高收缩压。只有一定舒张压，ＣＰＰ明显改善。更多还原

【Abstract】 Because coronary perfusion pressure (CPP) is lower which relates to survival rate in CPR , a novel CPR named as VDVEST - CPR was developed that was inflational vest assisted with enhanced external counter- pulsation (EECP ) during deflation. Methods : After 30 seconds of ventricular fibrillation both VDVEST - CPR and VEST - CPR were executed in random order on each of 8 dogs and alternated in 90 seconds inter- val. The statistical analysis used by paired - t test. Results : Mean systolic pressure of aorta in VDVEST - CPR was higher than VEST -CPR (10. 62±4. 23 kPa vs 9. 3± 4. 61kPa , P<0. 01 ) . The diastolic pressure of aorta (Pao ) and right atrium (Pra) in VDVEST -CPR were significantly higher than in VEST - CPR (P < 0. 01 ) , but the increament of diasotlic Pao was greater than that of diastolic Pra , so that CPP were im- proved significantly in VDVIEST - CPR ( P < 0. 0 1 ) . Maximum of CPP was increased 2 . 74kPa and mean of CPP was rise. 1. 89kPa. Conclusion : To compare with VFEST-CPR , VDVEST -CPR possessed the charac- ter of VEST which produced higher systolic Pao and the superiority of EECP which increased diastolic Pao , and improved CPP.更多还原