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小柴胡汤及其与青蒿素配伍的免疫学作用研究

Immunological Effects of Xiaochaihu Decoction and Its Combination with Artemisinin in Mice Infect-ed with Plasmodium berghei

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【作者】 王金华叶祖光薛宝云戴宝强肖永庆杨庆刘晓宏李泽琳屠国瑞

【Author】 Wang Jinhua;Ye Zuguang; Xue Baoyun;Dai Baoqiang; Xiao Yongqing;Yang Qing;Liu Xiaohong;Li Zelin;and Tu Guorui(Institute of Chinese materia Medica,China Academy of Traditional Chinese Medicine,Beijing,100700)

【机构】 中国中医研究院中药研究所

【摘要】 以伯氏疟原虫感染小鼠为实验模型研究了小柴胡汤、小柴胡汤与青蒿素(QHS)配伍用药的免疫学作用。研究结果表明:小柴胡汤或小柴胡汤与QHS合并用药均可显著提高疟疾小鼠的体液免疫、非特异性免疫、红细胞免疫的能力。对ConA诱导的淋巴母细胞转化有显著的免疫抑制作用。

【Abstract】 Effects of Xiaochaihu decoction alone and its combination with artemisinin(QHS)on immunological functions were studied in the mice infected with Plasmodium berghei.The data obtained in this study demonstrated that Xi aochaihu decoction and its combination with QHS exhibited significant immunos-timulation on humoral,nonspecific and red cell immunities. However,the con A一induced lymphoblastic transformation was remarkably depressed by the decoc-tion andits comhnation.

【关键词】 小柴胡汤青蒿素红细胞免疫
【Key words】 Xiaochaihu decoctionartemisininred cell immunity.
【基金】 93-95国家自然科学基金
  • 【文献出处】 中国实验方剂学杂志 ,CHINESE JOURNAL OF EXPERIMENTAL TRADITIONAL MEDICAL FORMULAE , 编辑部邮箱 ,1995年01期
  • 【分类号】R285.5
  • 【被引频次】6
  • 【下载频次】198
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