【摘要】 茯苓饮５００，１０００，２０００ｍｇ／Ｋｇ灌胃，对大鼠胃粘膜损伤有良好的保护作用，其中对盐酸和无水乙醇模型，茯苓饮高剂量优于ｃｉｍｅｔｉｄｉｎｅ（Ｐ＜０．０５，或Ｐ＜０．０１）。而在阿斯匹林模型上，在茯苓比不上ｃｉｍｅｔｉｄｉｎｅ。结果提示茯苓饮增强胃粘膜的屏障机能可能比对胃酸分泌的抑制作用更重要。更多还原

【Abstract】 The investigation has shown that Fuling decoction(FLD)has an excellent protective effect on drug一induced gastric lesions when orally given at dosages of 500, 1000 and 2000 mg/Kg( P<0.05 or P<0.01).FLD at high dose appears to be better than cimetidine for hydrochloric acid- induced model and ab-solute ethvl alco- hol- induced model.However,it is not as good as cimetidine for aspirin一induced model.The investigation indicates that the protective effect of FLD to gastric mucosa might be more important than the innibition to secretion of gastric acid.更多还原