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外源催产素(OT)在恒河猴的溶黄体作用位点
The Luteolytic Action of Oxytocin in the Rhesus Monkey
【摘要】 本文利用微量自动泵给恒河猴卵巢黄体连续注射催产素(Oxytocin,10miu/h)的局部在体实验,对催产素(OT)的溶黄体作用及机理进行了初步的研究.结果显示,OT注射后第2天其外周血的孕酮激素水平开始下降,而雌二醇(E2)则在处理后第总天开始下降(P<0.05)同时.OT的局部注射还能引起恒河猴月经周期黄体期明显缩短,使下一月经周期提前开始(P<0.01).实验表明,催产素(OT)在卵巢溶黄体过程中起着重要的作用,卵巢溶黄体作用的发生是通过其自身的分泌机制调节实现.
【Abstract】 The psper report the luteolytic action siteof ocytocin, using minipump-cannula sustem chronisally infused directly into the corpux luteum of normaly cyclic rhesus monkeys (Mac. mulatta). the results show infusion oxytocin can caused a significant (P < 0. 05) decrease in progesteron, beganing second day after treatnent and oestradiol after 4 days, the duration of luteal phase onset of menses from the initiation of oxytocin infusion were significantly (P<0.01) shorter when compared to thouse of vehicle-treaed controls, we suggest oxytocin play a important role.
- 【文献出处】 中山大学学报论丛 ,Supplement To The Journal of Sun Yatsen University , 编辑部邮箱 ,1995年03期
- 【分类号】Q49
- 【下载频次】26