【摘要】 在建立尿中补体抑制活性的检测方法的基础上，研究了ＳＬＥ患者尿中的补体抑制活性，结果发现活动性ＳＬＥ患者尿中补体抑制活性较正常人及非活动性ＳＬＥ患者明显增加。这种抑制活性具有部分耐热性，并与尿中红细胞计数及尿蛋白浓度间无明显平行关系。我们的研究结果表明ＳＬＥ患者尿中具有高水平的补体抑制活性，这一研究可能有助于加深对ＳＬＥ病理生理的认识，检测尿中补体抑制活性可能具有临床诊断价值。更多还原

【Abstract】 he detecting system for urinary complement inhibitory activity was eatablished and used inthe study of the urinary complement regulatory activity of SLE patients. A signficant incrcasedcompiement inhibitory activity was found in the urines from SLE patients as compared withthose from normal control and resting SLE. The activity was partially resistant to heat treatment(56℃ , 30min)and did not paralled with the urinary red blcod cell counting and protein concen-trations. This study might be helpful in deepening our understanding of pathogenesis of SLE,and the detection of urinary complement regulatory activity could have diagnostic values.更多还原