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脑损伤红细胞免疫功能变化及临床意义

The Changes of RBC immunity and clinical significance in acute closed head injury

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【作者】 孙志杨赵孟尧郭峰过宗南王文仲周晓平岳志健

【Author】 Sun Zhiyang; Zhao Mengrao; Guo zongnan; et al.(Deptment of Neurosnrgery Chanqhai HosPital The Second Millitary Medical University,Shanghai 200433)

【机构】 第二军医大学长海医院神经外科

【摘要】 检测66例急性闭合性颅脑外伤患者红细胞Cb受体花环率(RCbRR),红细胞免疫复合物花环率(RICR),红细胞免疫粘附促进百分率(RFER)及红细胞免疫粘附抑制百分率(RFIR)。观察各型脑外伤后免疫变化的规律与病情转归的关系。结果证明,各组脑外伤患者RCbRR和RFER均明显降低(P<0.01),而RICR和RFIR均明显升高(P<0.01);上述指标伤情越重,变化越明显,恢复越慢。讨论了发生机理及临床意义。

【Abstract】 Abstract The RBC immune adherence, which was determind by RBC C3b recepter rosetter (RC3bRR) and RBC immune complex rosetter (RICR) were measured in 66 patients with acute closed head injury. RBC immune adherence enhance factor rate (RFER), RBC adheence inhibitory factor rate (RFIR) were also measured. The relation between the changes of immune index of different types in head injury patients and prognosis of that were observed. The result showed that RC3bRR and RFER were significantly lower than that of control in each group. Whereas, RICR and RFIR were significantly higher than that of control. From comparing among groups, the more severity of injury, the remarkable the changes and the slower the recovery. The pathognesis and the clinical significance were discussed.

【关键词】 红细胞免疫脑损伤
  • 【文献出处】 中华神经外科杂志 ,CHINESE JOURNAL OF NEUROSURGERY , 编辑部邮箱 ,1995年03期
  • 【分类号】R651.150.2
  • 【被引频次】15
  • 【下载频次】27
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