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巨细胞病毒感染与先天肾积水关系探讨
Cytomegalovirus Infection and Hydronepbosis
【摘要】 对先天肾积水的病因研究以前主要着重于解剖和病理学方面。我们应用聚合酶链反应(PCR)技术直接检测手术中从肾盂内取的尿液及肾盂输尿管连接处的病变组织,结果25例患儿11例检测出巨细胞病毒(CMV)。对照组6例检测结果全部为阴性。二者经统计学处理结果有显著性差异(P>0.05)。提示CMV感染可能是引起先天肾积水的原因之一。
【Abstract】 Hydronephrosis is one of the common congenital abnormalities, but its pathogeny is not clear, We used polymerase chain reaction (PCR) to detect CMV in urine and the pathological tissues colected from the renal pelvis and ureter,11 out of the 25 hydronephrosis patients were positive (to CMV positive urine in 6 cases and positive pathological tissues in 8 cases). All specigested that CMV infection was associated with hydronephrosis and might be one of the causes to produce congenital hydronephrosis.
【关键词】 巨细胞病毒;
聚合酶链反应;
DNV.病毒;
肾/病毒学;
肾积水/病因学;
【Key words】 Cytomegalovirus; Hydronephrosis; Polymerase chain reaction;
【Key words】 Cytomegalovirus; Hydronephrosis; Polymerase chain reaction;
- 【文献出处】 中华实验和临床病毒学杂志 ,CHINESE JOURNAL OF EXPERIMENTAL AND CLINICAL VIROLOGY , 编辑部邮箱 ,1995年02期
- 【分类号】R512.990.2
- 【被引频次】4
- 【下载频次】29