【摘要】 观察了维甲酸对体外培养成纤维细胞DNA合成的影响,结果证明维甲酸对其合成有不同程度的抑制作用,呈剂量效应关系,并探讨了维甲酸治疗瘢痕的可能作用机理。更多还原

【Abstract】 The effect of retinoic acid on DNA synthesis of fibroblast was studied in vitro culture.The results demonstrated that retinoic acid significantly(P<0.01)inhi- bited the DNA synthesis of fibroblast in vitro culture and a dose-dependent relationship between DNA synthesis and retinoie acid concentration was observed.The possible mechanism of retinoic acid used for the treatment of sear was discussed.更多还原