节点文献
胃漂浮缓释片研究III核黄素胃漂浮缓释片
INTRAGASTRIC FLOATING AND SUSTAINED RELEASE TABLETS III RIBOFLAVIN TABLETS
【摘要】 以PVP、PVA为辅料的核黄素胃漂浮缓释片在体外能缓慢释药,人尿排药量试验表明该片生物利用度是普通片的1.58倍。溶出度与尿排药累积量相关。
【Abstract】 Sustained release and intragastric floating riboflavin(B2HBS) tablets based on PVP and PVA. were developed. The absorption study of the B2HBS tablets in six healthy human volunteers by urinary excretion method showed that the B2HBS tablets had a higher bioavailability than the conventional ones urinary excretion amount was relative to dissolution (at 25r/min).
【关键词】 核黄素;
PVP;
PVA;
胃漂浮缓释片;
溶出度;
尿排药累积量;
【Key words】 riboflavin; PVP; PVA; HBS tablets; dissolution; urinary excretion;
【Key words】 riboflavin; PVP; PVA; HBS tablets; dissolution; urinary excretion;
- 【文献出处】 中国医药工业杂志 ,CHINESE JOURNAL OF PHARMACEUTICALS , 编辑部邮箱 ,1995年06期
- 【分类号】R927.11
- 【被引频次】8
- 【下载频次】176