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脑干听觉诱发电位与异氟醚麻醉浓度定性及定量关系的研究

The clinical study of qualitative and quantitative relations between brainstem auditory evoked potentials(BAEP) and the inhaled concentrations of isoflurane.

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【作者】 张海波高崇荣熊希民陈敏

【Author】 Zhang Haibo, Gao Chongrong, Xiong Ximin, et al. (The Second Affiliated Hospital, Guangzhou Medical Collage, Guangzhou 510260.)

【机构】 广州医学院第二附属医院麻醉科!510260广州医学院神经研究所内科!510260

【摘要】 对10例患者研究了脑干听觉诱发电位(BAEP)潜伏期与异氟醚麻醉浓度定性及定量关系。全麻诱导采用2.5%硫喷妥钠(3~5mg/kg),阿曲库铵(0.6mg/kg)。气管插管后麻醉维持采用1.15%、1.73.%、2.30%异氟醚及60%N2O,肌松维持用阿曲库铵。记录麻醉前、诱导后,1.15%、1.73%、2.30%及减至1.15%异氟醚时BAEP峰潜期(PL)和峰间潜伏期(IPL)值。结果表明,BAEP波VPL能稳定反映异氟醚麻醉浓度变化,具有等级性并呈正相关关系,BAEPPL、各波正常值似可作为判断异氟醚麻醉深度的参考标准。

【Abstract】 The qualitative and quantitative relations between BAEP and concentrations of isoflurane were studied in ten selected patients. Anesthesia was induced with 2.5% thiopental 3-5mg. kg-1,and atracurium 0. 6 mg. kg-1. After tracheal intubation,anesthesia was maintained with a mixtune of isoflurane and 60%N2O. Muscle relaxation was maintained with intravenous atracurium 0. 6mg. kg-1.h-1. The peak latencies and interpeak latencies of BAEP were observed before anesthesia, and after anesthesin following isoflurane inhaled concentrations respectively at 1.15%, 1.73%, 2.30% and 1.15% In sequence. The results showed that there was a significant positive correlation between the peak latency of wave V and the corresponding concentration of isoflurane(p< 0. 01 ). The conclusion is that the peak latency of wave V may be considered as a paremetre for anesthesia depth.

  • 【文献出处】 中华麻醉学杂志 ,Chinese Journal of Anesthesiology , 编辑部邮箱 ,1995年09期
  • 【分类号】R614
  • 【下载频次】31
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