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大肠癌术后腹内复发的放射免疫显像研究

RADIOIMMUNOIMAGING OF INTRAPERITONEAL RECURRNCE FOR POSTOPERATIVE COLORECTAL CANCER

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【作者】 王振军才文彦张春丽潘中允

【Author】 Wang Zhenjun; Cai Wenyan; Zhang Chunli, et al (First Hospital, Beijing Medical Univeraity, Berjing 100034)

【机构】 北京医科大学第一医院外科

【摘要】 用131I标记抗癌胚抗原单克隆抗体(CEAMcAb)对临床难于诊断和处理的大肠癌腹内复发病变行放射免疫显像(RII).11例患者中10例为阳性,RII共检出≥2cm的癌症灶17/18处,假阳性、假阴性各1处.故其对≥2cm癌症灶的探测灵敏度和阳性图像的实际符合率均为94.4%.RII对血CEA阴性、隐匿性复发和腹内广泛播散者均有较高的诊断价值.RII还能判断复发癌是否侵犯膀胱.

【Abstract】 Abstract This study was designed to evaluate the usefuiness of RII for the diagnosis of intraperitoneal recurrent lesions of colorectal cancer. Of 11 cases examined. 10 were positive. RII found 17/ 18 recurrent lesions which is≥2cm, with 1false-positive and 1 fasle-negative lesion. Its sensitivity and predictive value of a positive scan were 94.4%. RII is of high value in disclosing seronegative and occult recurrent patients and the patients with wide spread intraperitoneal metastases. Also RII was effeetive in diagnosing whether the bladder was infiltrated by recurrent cancers.

  • 【文献出处】 中华核医学杂志 ,CHINESE JOURNAL OF NUCLEAR MDEICINE , 编辑部邮箱 ,1995年02期
  • 【分类号】R735.340.4
  • 【被引频次】3
  • 【下载频次】38
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