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医用胶原胶和胶原膜研制及临床应用

Study and Clinical Application of Medicinal Collagen Gel and Collagen Mambrane

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【作者】 马福广李芳彭燕豪刘锡麟甄兆忠梁佩红叶惠贞杨小红叶春婷孟博于致仁

【Author】 MA Fu guang,LIN Fang,PENG Yan hao,et al.Guangzhou Red Cross Hospital,Guangzhou 510220

【机构】 广州市红十字会医院创伤外科研究所

【摘要】 采用酸溶法提取哺乳类动物Ⅰ型胶原,胶原提取液透析纯化成为胶原胶,对角膜上皮愈合有促进作用。胶原提取液盐析精制成为胶原膜,对烧伤创面有减少渗出、减轻疼痛等作用。两种胶原制品对创伤组织修复的效果良好,缩短治疗期。其成分、药效、毒理等经各种实验验证,预计能广泛应用于临床。

【Abstract】 Native type Ⅱ collagen was isolated from rat tail tendon by acid extraction.Such an acid extract purified by dialysis became collagen gel which could promote cornea epithelial wound healing.Collagen membrane was made of the acid extract by salting out,it could decrease osmosis and lighten pains of burned wounds.The two type collagen preparations were efficient in repairing wound and shortening hospitalized period,and their composition,medicine effect and toxicity have been verified by a series of tests.It was supposed that the collagen preparations could be applied widely in clincal treatmemt.(Original article on page 149)

【关键词】 胶原角膜烧伤
【Key words】 Collagen Cornea Burns
  • 【文献出处】 中华创伤杂志 ,CHINESE JOURNAL OF TRAUMATOLOGY , 编辑部邮箱 ,1995年03期
  • 【分类号】R644
  • 【被引频次】27
  • 【下载频次】273
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