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衰老动物肠道菌群的变化及黄芪的拮抗作用

Changes of Intestinal Flora in Senility Mouse Modelsand the Antagonistic Activity of the Root of Astragalus membracem (Fisch.) Bge.

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【作者】 严梅桢宋红月谢念祥张粒民

【Author】 Yan Meizhen; Song Hongyue; Xie Nianxiang and Zhang Limin (Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Beijing 100700)

【机构】 中国中医研究院中药研究所

【摘要】 小鼠吸入臭氧(O_3),在体内诱发较强的自由基反应,导致一系列类似衰老的变化,复制出老龄小鼠模型,观察老龄小鼠肠道菌群的变化。并用黄芪水煎液灌喂衰老小鼠,结果表明,黄芪能使衰老小鼠紊乱的肠道菌群得以调整。

【Abstract】 Inhaled by mice, ozone induced stronger free radical reaction in the organism and led to a series ofchanges similar to senility. In this way the senility mouse models were established to observe the changes of intestinalflora in senile mice. The senile mice were given the root of Astrogolus membraceus decoction orally. The resultsshowed that the imbalance of intestinal flora in these mice was recovered.

  • 【文献出处】 中国中药杂志 ,CHINA JOURNAL OF CHINESE MATERIA MEDICA , 编辑部邮箱 ,1995年10期
  • 【分类号】R282
  • 【被引频次】33
  • 【下载频次】427
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