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肝癌治则机理实验研究

Experimentrtal Study on the Mechanism of Therapeutic Lawr of Liver Cancer

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【作者】 潘敏求孙兆泉刘礼意黎月恒唐湘娟

【Author】 Pan Min一Qiu,Sun Zhao一Quan,Liu Li-Yi,Li Yue一Heng,Tang Xiang 一Juan( H unan Acad emy of Trad i-tional Chinese Med icine and Materia Med ica (410006)

【机构】 湖南省中医药研究院

【摘要】 本实验主要观察了健脾理气、化瘀软坚、清热解毒法(A法),健脾理气法(B法),化瘀软坚法(C法),清热解毒法(D法)对小鼠肝癌的体内外抑瘤作用和对荷肝癌小鼠M细胞、NK细胞、LAK细胞、IFN、IL-2的影响。结果表明A法的直接抑瘤作用主要源于其中C法部分,对免疫功能的影响主要源于其中D法部分,A法为B,C,D法的有机结合。

【Abstract】 his Paper mainly studied the treatment of mouse hepatocarcinomas(H22)Which were vac-cinated by using four therapeutic methods of Traditional Chinese Med icine,that is,invigoratingthe splcen and rcgulating vital energy,removing blood stasis and dissipating a mass,clearingaway heat and toxic materials(A);invigorating the spleen and regulating vital energy(B)re-moving blood stasis and dissipating a mass(C)and clearing away heat and toxic materials(D)。Inhibition of tumour of mice was observed in vivo and in vitro respectively ,and the activity of M NkC, LAKC, IFN and IL一2 were determined in mice carring liver tumour by using theselaws。 The results indicated that the direct Lilling was mainly caused by the partc,the immunologicinfluence was mainly caused by the part B. The law of A is the organic comblination of B ,C andD,which can bring more anti一tumour action than other single law.

【关键词】 治法小鼠肝癌免疫学
【Key words】 theraputic law hepatocarcinoma mouse immunology
【基金】 国家自然科学基金
  • 【文献出处】 中国中西医结合外科杂志 ,CHINESE JOURNAL OF SURGERY OF INTEGRATED TRADITIONAL AND WESTERN MEDICINE , 编辑部邮箱 ,1995年05期
  • 【分类号】R273.57
  • 【被引频次】23
  • 【下载频次】139
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