【摘要】 在量－效和时－效关系上，醋氨酚（Ｐａｒ）ｉｐ能加速肝脏丙二本醛（ＭＤＡ）生成，增加血清ＭＤＡ含量，同时提高血清丙氨酸转氨酶（ＡＬＴ）活性。相关分析结果表明，血清ＭＤＡ含量的增加与上清ＡＬＴ活性变化之间存在正相关。抗氧化剂阿魏酸钠能减轻Ｐａｒ所致上述指标的改变。更多还原

【Abstract】 Paracetamol(Par)ip accelerated the formation of liver malondialdehyde(MDA) ,in-creased the content of serum MDA , and enhanced the activity of serum alanine transaminase(ALT) in the dose-response and time- response relationships。The data also indicated a fairly goodpositive correlation between serum MDA content and ALT activity. Pretreatment with antioxi-dant sodium ferulate could alleviate changes of the upper indexes in Par- treated mice.更多还原