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动态血压监测方法评价比索洛尔及阿替洛尔的降压疗效

ASSESSMENT OF BISOPROLOL AND ATENOLOL IN TREATMENT OF HYPERTENSION BY AMBULATORY BLOOD PRESSURE MONITORING

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【作者】 孙宁玲王静毅陈穗金周江云

【Author】 Sun Ning-Ling; Wang Jing-Yi;Chen Sui-Jin, et al.(Department of Cardiovascular Medicine,People’s Hospital,Beijing Medical University,Beijing)

【机构】 北京医科大学人民医院心内科

【摘要】 对40例原发性高血压患者采用24小时动态血压监测方法对β受体阻滞剂(比索洛尔、阿替洛尔)进行降压疗效的比较。结果显示:2种药物均能达到全天的降压疗效;比索洛尔24小时对收缩压及舒张压的降压作用强于阿替洛尔;比索洛尔24小时中对舒张压降低的百分率明显强于收缩压,并能在夜间保持持续降压状态;2种药物对心率的降低无差异性。这提示,比索洛尔的降压疗效(24小时1次口服)优于阿替洛尔。

【Abstract】 The comparative efficacy of oral bisoprolol(5 mg/day , n= 20)and atenolol(50 mg/day ,n= 20)in the treatment of hypertension had been assessed by 24 h ambulatory blood pressure monitoring. The results showed that hypertension could be controlled by both drugs. But the SBP and DBP were much reduced by bisoprolol than by atenolol,especially the DBP could be kept at normal level for all night. Heart rate showed no significant difference in both groups. Conclusion:The efficacy of bisoprolol in the treatment of hypertension seems much better than that of atenolol.

  • 【文献出处】 中国循环杂志 ,CHINESE CIRCULATION JOURNAL , 编辑部邮箱 ,1995年09期
  • 【分类号】R972.4
  • 【被引频次】10
  • 【下载频次】69
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