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不同浓度葡萄糖对猪胎胰β细胞发育的影响
Effect of different concentrations of glucose on the development of porcine fetal pancreatic β cells
【摘要】 采用不同浓度葡萄糖加入猪胎胰培养,观察其对猪胎胰β细胞发育的影响,结果显示:妊娠10~12周之猪胎胰β细胞,在不同浓度的葡萄糖环境中(2.8~11.2mmol/L),培养两周即可达到功能成熟,并以低糖环境(2.8mmol/L)为最佳,其急、慢性胰岛素的分泌均优于高糖(11.2mmol/L)及无糖环境。
【Abstract】 An experiment with different concentrations of glucose in cultures of porcine fetal pancreas was performed. The results showed that porcine fetal pancreatic βcells, of 10 ̄12 weeks gestation,matured in function in 2 weeks of culture in different concetrations of glucose(2.8 ̄11.2 mmol/L)and the low glucose medium (2.8 mmol/L) was the best. Acute and chronic insulin secretions from βcells cultured in that medium were better than those cultured in high glucose concentration (11.2 mmol/L) and in medium without glucose.
- 【文献出处】 中国糖尿病杂志 ,CHINESE JOURNAL OF DIABETES , 编辑部邮箱 ,1995年04期
- 【分类号】R587.1
- 【被引频次】7
- 【下载频次】28