【摘要】 本文报道卵巢原发性平滑肌来源的肿瘤5例,其中4例为平滑肌瘤,1例为平滑肌肉瘤。本文对卵巢平滑肌及平滑肌肉瘤的临床表现、病理学特征、诊断标准、组织学来源、鉴别诊断、治疗及预后作了论述。建议临床及病理医生在实践中给予重视以免漏诊和误诊。更多还原

【Abstract】 Objective:To clarify the clinical manifestation, pathological characteristics,diagnostic criteria,histo- logical origin,different diagnosis,therapy and progno- sis of ovarian smooth mascular tumors.Design:There were 5 cases in this study,including one leiomyosarco- ma and 4 leiomyoma.All specimans were embeded with paraffian,routinely sectioned and stained with HE;the histochemistry and immunohistochemistry were also studied.Results:The muscular fibrin of the tumor exhibited yellow color in vanGieson’s stain,and red color in Masson’s stain.The mark of Desmin (PAP)presented positive in leiomyoma and negative in leiomyosarcoma.The primary ovarian leiomyoma oc- cured in postmenopausal or menopausal women were often without any significant symptom.It is possible that the tumors originate from the smooth muscles of ovarian blood vessels,ovarian ligament,and ovarian mesenchymal tissue.The mitotic counts should be ma- jor evidence to diagnose the primary ovarian smooth muscular tumors which are benign or maligant.The hemorrhage,necrosis,and metastasis of the tumors al- so have diagnostic significance.Conclusion:The above results may play a role to help clinicians and patholo- gists to make accurate diagnosis of ovarian smooth muscular tumors.更多还原