【摘要】 本文对34例不孕症患者促排卵治疗进行了回顾性分析,其中16例采用克罗米芬(CC)/人绝经期促性腺激素(hMG)/绒毛膜促性腺激素(hCG)治疗,即 Chh 方案;18例采用促性腺激素释放激素激动剂(GnRH-a)/hMG/hCG 治疗,即 Gnhh 方案。结果:Gnhh 组83.33%患者用 GnRH-a 后,约在2～3周垂体卵巢功能被抑制,注射 hCG 前黄体生成素(LH)值明显低于 Chh 组(P<0.05),而 hMG 用量较 Chh 组多(P<0.05),所获成熟卵泡的总数、排卵周期及卵巢过度刺激综合征(OHSS)均明显高于Chh 组。研究结果表明,GnRH-a 能有效地抑制垂体及卵巢功能,Gnhh 方案可供常规排卵方案治疗失败再选择的促排卵方法之一。更多还原

【Abstract】 to determine the effect of GnRH—a on the women Suffering from anovular infertility.De- sign:34 women with abnormal and anovular menstru- ation were treated in our hospital.Chh group:16 of them were treated with clomiphen,human menopausal hormone(HMG)and human chorionic hormone (HCG).Gnhh group:18 of them were treated with GnRH—a,HMG and HCG.Results:The pituitary—o- varian function of 83.33% of the patients in Gnhh group were inhibited after they had been treated with GnRH—a for 2—3 weeks.The luteinizing hormon (LH)level was lower in Gnhh group than that in Ghh group(P<0.05).Gnhh group heeded more HMC than Chh group(P<0.05).The total number of mature ovum,ovulatary cycles and ovarian hyper—stimula- tion syndrome in Gnhh group were higher than that in Chh group.Conclusion:GnRH—a can effectively sup- press pituitary and ovarian function.The Gnhh scheme can act as a method of promoting ovulation af- ter the routine method failed to work.更多还原