【摘要】 本文对22例有排卵不孕妇女于 B 超监测排卵的同时,在卵泡中期、围排卵期和黄体中期测血清 LH、FSH、PRL、E₂、P、T;排卵后第10～14天取子宫内膜行病理学检查。按子宫内膜发育落后于月经周期>2天判断为黄体功能不全（LPD）。比较 LPD 组（n=12）和正常组（n=10）生殖激素值与卵泡直径的差异。结果;FSH 和卵泡期 LH、E₂在两组间无差异,黄体期 LH、E₂、P 水平,LPD 组低于正常组（P<0.05）;而 PRL、T 水平,LPD 组均高于正常组（P<0.05）。正常组卵泡直径大于 LPD 组（P<0.05）。结果提示 LPD 的发生与高 PRL、高 T 及黄体期低 LH 有关;卵泡发育不成熟也是 LPD 的原因之一。更多还原

【Abstract】 Serum LH,FSH,E₂,P,T,and PRL were measured during mid-follicular,periovulatory and middle luteal phase of the menstrual cycle,and B ultrasound were performed for detection of ovulation in 22 ovula- tory infertile women.Luteal phase defect（LPD）was definedas endometrial development being more than 2 days out of phase on biopsy.Comparison between the LPD group （n=12） and the normal group （n=10） showed no difference in terms of serum FSH,LH, and E₂ levels in follicular phase （P>0.05）.However, in luteal phase,serum levels of LH,E₂,and P in LPD group were lower than in normal group（P<0.05 ）whearas PRL and T levels in LPD were higher than in normal group（P<0.05）,and the follicular size in LPD group was smaller（P<0.05）.The results indi- cated that development of LPD was associated with high levels of PRL,T and low LH in the luteal phase.Abnormal follicuiogenesis may be another causitive factor for LPD.更多还原