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动态血压监测分析缓释维拉帕米和培哚普利的降压特点
Antihypertensive Feature of Slow Released Verapamil and Perindopril Monitored by Ambulatory Blood Pressure Measurement
【摘要】 采用3种血压测量方法[偶测血压(CBP),自测血压(SMBP),动态血压(ABPM)]对两组高血压病人进行2种缓释降压药比较(A组,缓释维拉帕米n=20;B组,培哚普利n=20)。结果提示,(1)治疗前,CBP与SMBP方法对血压的判断无差异,与ABPM方法比较有差别,治疗后,血压下降用3种方法比较,ABPM测量方法能明显区别夜间及白天血压变化,而CBP及SMBP方法则否。(2)用ABPM方法监测降压药物的效果,发现B组降低DBP强于A组,对SBP的降压两组药差异无显著性。
【Abstract】 Casual(CBP),self(SMBP)and ambulatory(ABPM)measurement were used in this study to compare the efficacies of 2 slow release antihypertensive drugs[(Group A-Isoptin SR(verapamil)n=20,Group B-Acertil(perindopril)n=20)] in hypertensive patients.The findings of this study indicate that:(1)Before treatment there is no difference of blood pressure determination between CBP and SMBP measurements,but there is a differcence between CBP,SMBP measurements and ABPM,After the treatment,ABPM method is able to find the difference of blcod pressure between day time and night time,while CBP and SMBP not;(2)ABPM method indicates the Acertil is more effective in lowering DBP than Ipsotin group,but no difference of reduction in SBP between two drug groups was found.Conclusion:ABPM method may precisely analyse the hourly changes in blood pressure.
- 【文献出处】 高血压杂志 ,Chinese Journal of Hypertension , 编辑部邮箱 ,1995年03期
- 【分类号】R544.1
- 【被引频次】3
- 【下载频次】33