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萘丁美酮用于骨科疾患抗炎镇痛380例
Anti-inflammatory and analgesic effects of nabumetone in treatment of orthopedic diseases in 380 patients
【摘要】 目的:观察非甾体消炎镇痛药萘丁美酮对骨科疾患抗炎镇痛的疗效。方法:380例骨科疾病病人(男性221例,女性159例),平均年龄49±s11a,用萘丁美酮治疗1-2g/d,po,10d为一个疗程。结果:1-6mo随访结果表明,其对骨关节炎、坐骨神经痛以及急性软组织损伤等的总有效率为76.8%,消化系统的轻度不良反应发生率为1.8%。结论:该药疗效与所治疾患、疗程、停药时间及服药方法有关,具有镇痛消炎作用强、持续时间长、服用方便和不良反应少的特点。
【Abstract】 AIM:To survey the therapeutic effect of nabumetone in treating orthopedic diseases.M ETHODS:Three hundred and eighty patients(M 221,F159)with various orthopedic diseases were treated with nabumetone,1-2g/d,po,10d as a course. RESULTS: The patients were followed for 6 mo. The total effective rate of osteoarthritis,sciatica and acute soft tissue injuries was 76.8%,the adverse reaction incidence rate of digestive system was 1.8%.The therapeutic effect was related to the kind of diseases,courses of treatments,withdrawal times and methods of taking medicine.CONCLUSION:Nubumeton is an analgesic and anti-inflammatory agent with stronger,and more lasting actions in comparison with similar products.The adverse effects are mild.
【Key words】 nabumetone; osteoarthritis; analgesia; non-steroidal anti-inflammatory agents;
- 【文献出处】 新药与临床 , 编辑部邮箱 ,1995年03期
- 【分类号】R971.1
- 【被引频次】3
- 【下载频次】45