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奥曲肽治疗慢性肾功能衰竭并发的上消化道出血
Octreotide in treating peptic ulcer hemorrhage in patients with chronic renal failure
【摘要】 慢性肾功能衰竭合并胃镜证实消化道大出血7例(男性3例,女性4例;年龄54±s9a)。腹膜透析病人用奥曲肽0.1mg加25%葡萄糖液20mL,iv0.4-0.5mg加10%葡萄糖液1000mL,ivgtt,24h,用至粪隐血阴性;血液透析病人用0.1mg加25%葡萄糖液20mL,iv,0.1mg,sc,q8h或q12h,用至粪隐血阴性。全部止血成功,未见明显副作用。
【Abstract】 Effect of octreotide on 7 patients(M3,F4;age54±s9a)with chronic renal failure complicated with peptic ulcer bleeding proved by gastrofiberscope was investigated.The patients with peritoneal dialysis received octreotide 0.1 mg in 25% glucose 20 mL,iv, then 0.4-0.5 mg in 10% glucose 1000 mL,iv gtt,for 24 h until melena disappeared.The other patients with hemodialysis received octreotide 0.1 mg in 25% glucose 20 mL,iv,then 0.1mg,sc,q8h or q12h until melena disappeared.The results showed that the bleeding was stopped successfully in all 7 patients and no obvious adverse reactions were seen.
【Key words】 octreotide; Chronic kidney failure; peptic ulcer hemorrhage;
- 【文献出处】 新药与临床 , 编辑部邮箱 ,1995年03期
- 【分类号】R692.505
- 【被引频次】3
- 【下载频次】33