【摘要】 本文对同济医院近15年收治的1765例女性生殖系统恶性肿瘤病例进行了回顾性研究，结合临床与病理资料，确诊8例为女性生殖系统多原发性恶性肿瘤，并对这8例患者的临床待征、病理特点、治疗及转归进行了系统的分析。结果发现：其发生率占女性生殖系统恶性肿瘤的0．45％，以同时累及卵巢和子宫最多见，占50％；病理类型在上生殖道以腺癌为主，下生殖道则以鳞癌为主；获得早期诊断的患者，经过积极治疗后，预后较好。同时本文还对多原发性恶性肿瘤的诊断方法和标准进行了阐述。目前主要依靠临床病理学方法。细胞DNA含量流式细胞术、免疫组织化学染色等技术对多原发性恶性肿瘤的诊断有一定帮助，担由于存在交叉现象，仍有较大局限世。更多还原

【Abstract】 During the Period from 1978 to 1993, 1765 patients with primary malignant tumor of the fernale reproductive tract were ad-mitted to Tongji hospital. Eight of them were diagnosed as mutiple primary malignant tumor (MPC) of the female reproductive tract, accord-ing to clinical and Pathological material. By systemic analysis, the results shOwed that: In the primary malignant tumors of the female repro-ductive tract, the rate of MPC was 0. 45 %, and 50% of them involved the ovaries and the uterine corpora simultansously. Pathologically, the majority of upper reproductive tract tumos were adenocarcinomas, while the majority of lower reproductive tract tumors were squamous cell carcinomas. After treatment, the prognosis of patient of MPC was favourable. The diagnostic criterion and methods were also discussed in this paper. Until now. pathology examination was still the main rnethed to dignose MPC. Flow cytometric DNA-ploidy analysis and imrnunohis-tochemical stains were useful to diagnosis, but they were limited because of the overlapping phenornenon.更多还原