节点文献
去甲斑蝥素合成工艺的改进
IMPROVEMENT ON SYNTHESIS OF NORCANTHARIDIN
【摘要】 去甲斑蝥素显一种具有升白作用的新型抗肿瘤药物,由呋喃与马来酐按Diels-Alder加成反应后催化氢化制得。本工艺改变反应溶媒、物料配比及催化剂条件后,总收率可达95.8%以上。
【Abstract】 Norcantharidin is a kind of new-type anticancer drug with the effect of inereasing white cells. It was sythesized with furane and maleic anhydride through Diels-Alder reaction. By changing the solvent, the ratio of materials catelyst, its overall yield was increased to 95. 8%.
- 【文献出处】 天津药学 ,Tianjin Pharmacy , 编辑部邮箱 ,1995年02期
- 【分类号】TQ463
- 【被引频次】16
- 【下载频次】302