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153Sm—EDTMP 治疗继发性恶性骨肿瘤的临床观察

The Clinical Effects of 153 Sm-EDTMP onTreating Malignant Skeletal Metastasis

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【作者】 姜藻戴梅美朱梁军徐勤炬

【Author】 JiangZao; Dai Me-niei; Zhu Nian-jun;et al. (De-partment of Oncology, Affiliated Hospital ofNanjing Rallway Medical College)

【机构】 南京铁道医学院附属医院肿瘤科

【摘要】 153Sm—EDTMP治疗继发性恶性骨肿瘤36例(剂量37MBq/kg).36例中,轻度疼痛者7例,中度疼痛者19例,重度疼痛者10例。治疗后,疼痛消失者9例,减轻者16例,缓解者9例,2例无效。疼痛消失者均为轻中度疼痛,总有效率为94.4%。平均有效期为24.7±20.3天。大多数病例血常规、肝功和肾功无显著变化。

【Abstract】 e surveied the clinical effects of 153Sm-EDTMP aderministered in 36 cases ofpatients with malignant skeletal metastasis.According to extent of bone pain , these caseswere divided into 3 groups , mild pain in 7 cas-es , moderate pain in 19 cases’ serious pain in10 cases, After administration of the agent,94. 4% of the patients with skeletal pain dueto disseniinated bone emetastasis were imporved, disappeared in 9 cases, marked reliefin 16 cases. slight improved in 9 cases; 2 ofpatients were invalidaty. Mean duration onthe efficaciouseness was 24. 7 ± 20. 3 days.There were not significant anonialous changesin WBC and platelet counts as well as liverand kidney functions in most of the patients.

  • 【文献出处】 铁道医学 ,RAILWAY MEDICAL JOURNAL , 编辑部邮箱 ,1995年02期
  • 【分类号】R738.1
  • 【被引频次】1
  • 【下载频次】9
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