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冷冻精液人工授精成功率及其影响因素

Artificial insemination with frozen donor′s semen and factors affecting its success rate

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【作者】 梁小薇沈和谷翊群吴志刚李鸿卢文红陈振文

【Author】 LIANG Xiaowei,SHEN He,GU Yiqun,WU Zhigang,LI Hong,LU Wenhong,CHEN Zhenwen National Research Institute for Family Planning ,Beiling 100081

【机构】 国家计划生育委员会科学技术研究所

【摘要】 本研究对由于男性原因所致不育,而女方生殖功能正常的48对夫妇进行供者冷冻精液的人工授精治疗6个周期,总成功率62.5%,总周期成功率21.4%,流产率3.3%,6个月末累积成功率63.65%,成功者平均所需周期1.9±1.1。成功率随妇女年龄增长呈下降趋势,女方潜在生殖功能异常和中断治疗对成功率也有重要影响。

【Abstract】 bjective:To analyse the factors affecting the treatment of male infertility by artificial inseminationwith frozen donor′s semen.Design :Clinical study.Setting:The Male Clinical Research Laboratory of National Research Institute for Family Plannin.Subjects :Forty- eight infertile couples due to male factors were studied.The wives had normal repro-ductive function.Methods:Artificial inseminations were performed with frozen donor′s semen for 6 cycles.Results:After treatment the pregnancy rate was 62.5%,the successful rate per cycle was 21.4%andabortion rate was 3.3%.the cumulative pregnancy rate was 63.65%at end of 6th month.Twenty- six of30 pregnant women were conceived within the first 3 treatment cycles with an average of 1.9±1.1 treat-ment cycles.Conclusion :The successful rate tends to declive with the increase of women’s age.In addition ,thewives′normal reproductive function and continuous treatment for several cycles are essential factors affectingthe pregnancy rate.

【基金】 国家计划生育委员会“七五”资助
  • 【文献出处】 生殖医学杂志 ,JOURNAL OF REPRODUCTIVE MEDICINE , 编辑部邮箱 ,1995年03期
  • 【分类号】R698
  • 【被引频次】1
  • 【下载频次】56
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