【摘要】 本文对２５例老年肺心病患者的免疫指标检测结果表明，与健康老年人相比，发作期患者ＣＤ３、ＣＤ４、ＣＤ８及ＣＤ４／ＣＤ８均显著低下（Ｐ＜０．０１～０．０５）；ＲＢＣ＋Ｃ３ｂＲＲ显著低下，而ＲＢＣ－ＩＣＲ显著升高（Ｐ＜０．０１）；ｓＩＬ－２Ｒ显著升高（Ｐ＜０．０１）；体液免疫指标除Ｃ３显著低下外，ＩｇＧ、ＩｇＡ、ＩｇＭ及ＣＩＣ显著升高（Ｐ＜０．０１）。经相关分析发现，ＣＤ４／ＣＤ８与ＲＢＣ＋Ｃ３ｂＲＲ及Ｃ３呈高度正相关，而与ＣＩＣ呈高度负相关。经治疗缓解后上述指标均呈相对应负性改变，且上述相关性消失。提示动态观察上述指标对判断临床状态及为患者提供免疫治疗有一定的价值。更多还原

【Abstract】 We determined immunological indices in 25 elderly patients with chronic cor pulmonale.The results,comparing with 20 healthy old people,showed that during the exacerbation stage:(1)the counts of CD3 ,CD4 and CD8 and the ratio of CD4/CD8 decreased remarkably (P<0.01/0. 05);(2) the perentage of RBC-C3bRR was significantly lower,while those of RBC-ICR and the level of sIL-2R were significantly higher (P<0. 01);(3) the humoral immunological indices,IgG,IgA,IgM and CIC levels,increased notably,while C3 decreased notably (PM0.01);(4)there was a significant positive correlation between CD4/CD8 ratio and RBC-C3bRR as well as C3 level, but there was a significant negative correlation between CD4/CD8 ratio and CIC level. During the remission stage after treatment,all the abovementioned indices changed significantly to their corresponding opposites.This indicated that the present observation had some value in the clinical judgement and immune treatment for the diseases.更多还原