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免疫酶法检测血清EB病毒─IgA/VCA对鼻咽癌诊断的价值

Valre of Detection of Serum Epstein─Barr Virus IgA/VCA by Immunoenzyme Technique in the Diagnosis of Nasopharyngeal Carcionma

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【作者】 肖远康张洁陆燕蓉林苹

【Author】 Xiao Yuankang,Zhang Je,Lu Yianrung,et al(Institute of Cancer Research,West China、Univesityof Medical Seiences,Chengdu, 610044)

【机构】 华西医科大学肿瘤研究所

【摘要】 应用免疫酶法对放疗前鼻咽癌病人990例、放疗后临床缓解鼻咽癌病人1168例、放疗后复发的鼻咽癌病人76例、头颈部其它恶性肿瘤病人96例、鼻咽部非癌疾病2192例和正常人2321名血清的EB病毒IgA/VCA抗体进行了检测,阳性率分别为95.95%、77.39%、98.68%、32.29%、12.54%和0.17%。结果提示免疫酶法检测IgA/VCA抗体对鼻咽癌诊断及监测病情有重要的临床价值。

【Abstract】 Serum Epstein─Barr virus(EBV)IgA/VCA were detected hy immunoenzyme techniquein 990 nasopharyngeal carcinoma(NPC)patients before radiation,1168 NPC patients after raditqtion withremission,76 NPC patients after radiation with recurrence, 96 patients with other maligiiancies of headand neck. 2192 patients with nonmalignant diseases of nasopharynx and 2321 normals. The positive rate ofserum EBV─IgA/VCA were 95.95%,77.39%, 98.68%,32.29%, 12.54%and 0.17%,respectively.The results suggest that the detection of serum EBV─IgA/VCA by immunoenzyme technique is of greatvalue in clinical diagnosis of NPC and monitoring deveopment of disease.

  • 【文献出处】 实用癌症杂志 ,THE PRACTICAL JOURNAL OF CANCER , 编辑部邮箱 ,1995年01期
  • 【分类号】R739.63
  • 【被引频次】5
  • 【下载频次】50
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