【摘要】 本文应用彩色多普勒超声心动图(CDFI)检测酚妥拉明降低25例室间隔缺损(VSD)合并肺动脉高压(PH)患儿的肺动脉收缩压(PASP),观察酚妥拉明使用前后PASP的下降程度,并提出判断VSD+PH是可逆性的、交界性的或永久性的标准。结果表明:使用酚妥拉明后,PASP较用药前下降3.3kPa(25mmHg)以上为可逆性的肺动脉高压,共13例,均经手术修补后痊愈出院,PASP较用药前下降2.6～3.3kPa(20～25mmHg),为交界性肺动脉高压,共8例,其中4例做修补术,术后均合并肺部感染,1例还出现肺不张,均经保守治疗痊愈出院,PASP较用药前下降2.6kPa(20mmHg)以下,为永久性肺动脉高压,共4例,其中2例手术修补均死亡。此药物试检结果可以指导手术治疗,预测手术效果及患儿预后。更多还原

【Abstract】 we detected Regitine in reducing pulmonary artery systolic pressure(PASP)in 25 patients with ventricular septal defect (VSD) complicated with pulmonary hypertension (PH)by color Doppler flow imaging(CDFI). We judged that the degree of VSD+ PH was reversible, intersected or permanent according to reducing degree of PASP before and after using Regitine and the patients’ postoperative condition. This result indicates: reversible PH-PASP after the experiment was decreased by 3. 3 Kpa and the patients were discharged from hospital after recovery? intersected PH-PASP by 2. 6-3. 3 kpa and the patients engendered lung complication after repair;permanent PH-PASP by less than 2. 6 Kpa and the patients died after operative repair.更多还原