【摘要】 ５０例经病原学确诊的免疫抑制患者（ＩＣＨ）肺部感染，其中３６例生前诊断，１４例死 后经尸解或肺穿刺确诊。行全套病原学（除巨细胞病毒，ＣＭＶ）检查的４１例中普通细菌１９例 （４６．３％）、结核杆菌１０例（２４．４％）、真菌８例（１９．５％）、卡氏肺孢子虫（ＰＣ）４（９．８％），明显有别 于免疫机制正常患者肺部感染的病原分布。混合感染率为１８．０％。病死率５８．０％（２９／５０）。基础 疾病、免疫抑制治疗疗程、混合感染、病原体种类、血白细胞计数、病变范围与本病预后相关，而 性别、年龄、免疫抑制剂种类、体温与预后无关。着重强调了生前尽早行病原学采样和检查对 ＩＣＨ肺部感染诊断及治疗的重要性。更多还原

【Abstract】 Fifty eases of pulmonary infections in immunocompromised patients were reported. 36 of them were diagnosed daring life, other 14 cases were diagnosed by autoposy and/or postmortal lung puncture. Serial etiological agents (except cytomegalovirus) were examined in 41 patients: common bacteria 19(46.3%). mycobacterium tuberculosis 10 (24.4%), fungus 8(19.5%), pneumocystis carinii 4(9.8%), the etiological agents distribution in immunocompromised patients differ from that in immunccompetent patients. Mixed infection rate was 18.0%. The mortality was 58.0%. Underling diseases, duration of immunosuppressive therapy, extent of lesions, mixed infection, type of etiological agents, white blood cell count were related to mortality; age, sex, temperature, types of immnnosuppression were not related to mortality. The significance of executing etiological samplings and examination during life as soon as possible for the diagnosis and treatment of pulmonary infections in immunocompromised patients was emphasized.更多还原