【摘要】 竹红菌甲素在脂质体中的光谱性质和结合能力研究邹伟，安静仪，蒋丽金（中国科学院北京感光化学研究所，１００１０１）关键词竹红菌甲素；光谱特性；结合；脂质体竹红菌甲素（Ｒ人）是一种新型并配类光疗药物，临床上治疗一些皮肤病效果显著”’，研究表明ＨＡ对癌细胞有...更多还原

【Abstract】 The absorption and fluorescence spectral properties of hypocrellin A(HA) bound to egg phosphatidylcholine (EPO) liposomes were studied and compared with those in organic solvents. It indicates that HA in bilayer remains its initial structure. It has been shown that the location and the intensity of fluorescence are related to the concentrations of HA. EPC and the pH of the buffer solution.The binding constant of HA to lipid membrane was measured to be 7.01(mg/ml)-1. HA was found to be mainly partitioned on the surface of the lipid membrane as demonstrated by fluorescence quenching experiments.更多还原