【摘要】 对变形链球自Ｉ型Ｓ．ｍｕｔａｎｓＭＴ，Ｒ（血清型Ｃ）菌株表面蛋白Ｐ１分离、纯化、鉴定，经１３１Ⅰ标记后，研究其对无龋成人腮腺唾液膜的粘附性，共观察２２例。结果显示，蛋白Ｐ１能直接粘附于唾液膜，在唾液膜上的粘附量显著大于牛血清白蛋白膜和缓冲液处理的羟磷灰石组（Ｐ＜０．０１），提示蛋白Ｐ１可能是变形使球菌遗传Ⅰ型、血清Ｃ型的重要粘附素之一。更多还原

【Abstract】 In this study , the surface protein P1 of Streptococcus mutans MT6R (serotype C) was extracted from the culture supernants , purified by PAGE, identified by the standard antisera and labelled by with 131I. The adherence of 131 Iprotein P1 (131I - P1 ) to the saliva-coated hydroxyaptite (S-HA)of the CF(caries-free , 22 ,DFS= 0)were studied. The adhesion of 131I-P1 to the S-HA promoted to a greater extent than that to the HA treated with buffer and bovine serum albumin (P < 0. 01 ). This result suggested that protein P1 may be one of the important adhesins of S. mutans.更多还原