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家兔在体心脏的房室传导特性

Atrioventricular Conduction Property of the in Situ Rabbit Heart

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【作者】 钮伟真刘北英焦晓慧

【Author】 Niu Weizhen; Liu Beiying;Jiao Xiaohui(Department of Cardiovascular Physiology,Capital Institute of Medicine)

【机构】 首都医学院心血管生理研究室

【摘要】 应用程控心房期前刺激、快速心房起搏,或并用心得安的方法,进一步研究了家兔在体心脏功能性房室传导阻滞产生的部位和特点。实验中发现家兔功能性房室传导阻滞主要发生在希浦系(His-Purkinjesystem)。结果提示,家兔心脏在体条件下的房室结可能不具备滤波特性,而希浦系在一定程度上可防止过多或过早的室上性冲动侵入心室。

【Abstract】 Many studies have suggested that the atrioventricular node(AVN)can blockexcess or early premature atrial impulses and prevent from the ventricular fibrillation.This function is termed filtering property(FP)of the AVN.The aims of this study were to investigate the site of the functional A-V block(FAVB)and FP of the atrioventricular conduction tissues in the rabbit heart in situ by means of programmed atrial stimulation,rapid atrial pacing,recording of the His-bundle electrogram and treatment with propranolol.We found that the FAVB occurred mainly at the His-Purkinje system(HPS).The results indicate that the AVN of the in situ rabbit heart may not have FP while the HPS can prevent to a certain extent excess or earlier supraventricular impulses from exciting the ventricle.

  • 【文献出处】 首都医学院学报 ,Journal of Capital University of Medical Sciences , 编辑部邮箱 ,1995年02期
  • 【分类号】R331.38
  • 【下载频次】23
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