【摘要】 在８０例Ⅱ型糖尿病患者，观察了正中神经和胫后神经刺激引起的脊髓诱发电位（ＳＣＥＰ）。结果表明，糖尿病患者ＳＣＥＰ的Ｎ＿（１３）、Ｎ＿（２０）潜伏期均比正常人明显延长（ｐ＜０．００１），并可发现无神经病变征象的亚临床型神经损害；同时，Ｎ＿（１３）、Ｎ＿（２０）潜伏期与病人的病程、病情及神经病变征象呈正相关（ｒ＝０，２５－０．５８，ｐ＜０．０５－０．０００１）．而与空腹血糖水平无关（ｒ＝０．０５－０．１１，ｐ＞０．０５）。提示ＳＣＥＰ检查有助于糖尿病神经病变的早期诊断和疗效观察。更多还原

【Abstract】 The SCEP elicited by median and posterior tibial nerve stimulation were observed in 80 cases of type-Ⅱ diabetic patients and 52 age matched healthy hu-men.These results indicated that latencies of wave N₁₃and N₂₀ in SCEP were signifi cantly longer in diabetic patients than in healthy healthy humen （P<0.001 ）,even in the patients there had no signs of neuropathy , the subclinic nerve damage could also be revealed;fur-thermore,the latency of wave N₁₃ or N₂₀ was correlated with the duration and severity of diabetes and the signs of neuropathy（r=0.25-0.58.p=0. 0274-0. 0001 ）except for the blood sugar level in empty state （r=0.50-0. 11.P=0.3361-0.6499）.These re-sults suggested that wave N₁₃ and N₂₀ latencies in SCEP can be used as a powerful marker of early diagnosis and follow -up of treated effects on diabetic peripheral neuropathy.更多还原