【摘要】 自１９７５年至１９９１年，３０８例肝细胞癌患者行根治性切除术，术后１，２，３，４，５和１０年的复发率分别为１２．７％，２８．７％，４１．２％，４７．４％，５４．１％和６４．４％。到１９９２年３月，共有１３４例复发。复发的危险因素经Ｃｏｘ模型分析，单因素分析发现高的ｒ－ＧＴ，发现途径，严重的肝硬化，门静脉癌栓，局部切除术为复发的危险因素。经多因素分析后发现，只有高的ｒ－ＧＴ，严重的肝硬化，局部切除术与复发有统计学意义。作者认为严重的肝硬化妨碍了肝切除的范围，局部切除术后的综合治疗可减少复发更多还原

【Abstract】 hree hundred and eight patients with hepatocellular carcinoma underwent radical resection during 1975-1991.The 1-,21,3-,4-,5-,and 10-year recrrent rate were 12.7%28.7%,41.2%,47.5%,54.1%,and 64.4%%respectively. By the end of March 1992,recurrence had Occurred in 134 patients. Risk factors for recurrencewere analyzed.Cox univariate analysis identified the following five factors to be correlated with increasing risk:high r-GT,discovery by clinical,macronodular cirrhsis, minor resection and portal vein embolus.However onlyhigh r-GT,macronodulaar cirrhosis,and minor resection have been proved significant risk factors for recurrencein Cox multivariate anaaiysis.Cirrhosis interfers with major hepatic rcsection,comprehensive treatment intra-and/or post-operation might reduce recurrence.更多还原