【摘要】 本文研究94例甲状腺癌之326个局部引流区非转移淋巴结形态改变,结果表明①恶性度低预后好的乳头状癌及髓样癌的局部淋巴结组织学分型主要为Ⅰ型和Ⅱ型,而恶性度高预后差的未分化癌和滤泡癌则主要为Ⅲ型和Ⅳ型,x~2=16.69,P<0.01。②淋巴结内组织细胞、浆细胞在乳头状癌及髓样癌的改变主要为Ⅲ级和Ⅳ级,未分化癌和滤泡癌则以Ⅰ级和Ⅱ级为主,x~2=17.23和10.67,P均<0.01。③淋巴结内小血管的改变在乳头状癌及髓样癌以管壁增厚及内皮细胞增生为主,滤泡癌及未分化癌则以薄壁型血管为主,x~2=9.25,P<0.01。④淋巴窦扩张若发生在组织细胞增生增多之基础上,具有一定抗肿瘤防御反应的意义,否则意义不大。⑤观察癌肿引流区非转移淋巴结的组织学改变,不但能了解该淋巴蛄所处的“戒备状态”、宿主的免疫状况及抗肿瘤反应能力,而且能预示肿瘤临床预后。更多还原

【Abstract】 326 non -transferring Lymph node morphological changes in the local drainage of thyroid cancer in 94 cases have been studied ,the results are as follows:1) Type Ⅰ and type Ⅱ were found lymphohistologically in papillary and medullary carcinoma with low malignity and better prognosis ,while Type III and Type IV in undifferenti-ated and follicular carcinoma with high malignity and bad prognosis , x2 = I6. 69 ,P<0. 0I.2) Changes in the lymphohistocyte and plasmocyte of papillary and medullary carcinoma were mainly of Type -III and Type IV ,and Type I and Type II were found in undifferentiated and follocular carcinoma ,x2 = I7. 23 and I0. 67 ,P<0. 0I.3)Changes in the fine blood vessel in the lymph node of papillary and medullary carcinoma are mainly of pachynesis in the vessel wall in follocular and undifferentiated carcinoma ,x2 = 9. 25 ,P<0. 0I.4)Occurrence of lymphoid sinus delatation in histocytosis is of "preventive reaction "to carcinoma ,but not very significant.5)Study on non -transferring lymphohistological changes the drainage region of carcinoma will not only make clear the lymph node"on the alert"and host immune response to carcinoma but the suggestion of clinical prognosis of carcinoma as well.更多还原